Isadora Ritter Müller, Gabriel Linden, Mariele Feiffer Charão, Marina Venzon Antunes & Rafael Linden • June 12, 2023

Dried blood/plasma spot sampling for therapeutic drug monitoring: challenges and opportunities

A recent publication in Expert Review of Precision Medicine and Drug Development highlights DBS as a reliable and increasingly validated tool for drug monitoring in chronic and complex therapies.

💡 DBS is more than a new sampling method. It transforms how we collect, transport, and analyze pharmacological data — unlocking strategic advantages for:


👩‍⚕️ Patients:

  • Minimally invasive, fingerstick-based collection
  • Enables home-based sampling
  • Improves comfort and treatment adherence



🩺 Clinicians and care systems:

  • Allows more frequent and consistent drug level monitoring
  • Supports precise dose adjustments
  • Expands monitoring reach to underserved regions



🏭 Pharma industry:

  • Accelerates phase 3 and post-market studies with decentralized data
  • Lowers logistical costs and infrastructure burden
  • Increases diversity in clinical cohorts — essential for variable-response drugs
  • Generates real-world data in naturalistic settings


At Health ID, we develop capillary sampling solutions that support TDM with stable, standardized collection and full lab compatibility — helping bridge innovation with real-world application.



The future of TDM is scalable, accessible, and powered by smart sampling.


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